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General description A cell-permeable, potent, selective, and reversible MMP-9 Inhibitor (IC50 = 5 nM). Inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 (IC50 = 113 nM) only at much higher concentrations. A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 IC50 = 113 nM) at higher concentrations. Biochem/physiol Actions Primary Target MMP-9 Warning Toxicity: Standard Handling (A) Reconstitution Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Other Notes Levin, J.I., et al. 2001. Bioorg. Med. Chem. Lett.11, 2189.
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