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Cyclopiazonic acid from Penicillium cyclopium has been used:. as a standard in aflatoxin detection and quantification by thin layer chromatography (TLC). as a component in Ca2+-free DMEM/10% fetal bovine serum (FBS). as a reversible inhibitor of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) to examine the role of luminal calcium in endoplasmic recticulum (ER)-to-Golgi trafficking. as an endoplasmic reticulum Ca2+-ATPase blocker, to treat neurons and also to study the role of the endoplasmic reticulum (ER) in releasing and sustaining Ca2+ during Ca2+-induced Ca2+ release (CICR) to inhibit SERCA
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