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5-Hydroxy-1,4-naphthoquinone (juglone) can be used as a starting material for the synthesis of:. Trypanocidal drugs.. Tacrine-naphthoquinone hybrids with potential application in the treatment of Alzheimer鈥瞫 disease.. Juglone-based electroactive polymer, poly(5-hydroxy-1,4-naphthoquinone-co-5-hydroxy-3-thioacetic acid-1,4-naphthoquinone), for the electrochemical detection of DNA hybridization.. Ent-nocardione A, naturally-occurring tyrosine phosphatase inhibitor.Juglone can also be used as a dienophile in the Diels-Alder reaction for the synthesis of variety of C-aryl glycosides.
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