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Isonicotinic acid (IN) can be used as:. An organocatalyst in the one pot four component condensation reaction, to synthesize pyranopyrazoles based heterocyclic compounds.. An organic ligand for the preparation of copper(I) halide coordination polymer [CuBr(IN)]n, by hydrothermal method.. As a starting material for the synthesis of cation-dimers with potent antimalarial activity.