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2-Pyridinecarboxaldehyde has been used:. To synthesize chitosan based bifunctionalized adsorbent.. In the aldol addition reaction with pyruvate in the presence of 2-keto-3-deoxy-6-phosphogluconate aldolase (KDPG) catalyst to form (S)-4-hydroxy-2-keto-4-(2鈥?pyridyl)butyrate.. In the condensation reaction with (S)-(鈭?-伪-methylbenzylamine and (R)-(+)-伪-methylbenzylamine to synthesize two chiral (S)-(鈭?- and (R)-(+)Schiff base compounds.It can also be combined with thiosemicarbazide to form 2-pyridinecarboxaldehyde thiosemicarbazone ligand (L) which can further complex with Ni(II) and Cu(II) salts (MX) to form [M(L)2X2] complexes.